ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0015629
Name	actin cytoskeleton
Type	Cellular Component
No. of Genes in ADHDgene	26
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 26)

Literature-origin genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	4q21.3-q22	1(0/1/0)	IDA[17408955]
BAIAP2	BAI1-associated protein 2	17q25	1(1/0/0)	IDA[19366662]
CTNNA2	catenin (cadherin-associated protein), alpha 2	2p12-p11.1	2(1/1/0)

Genes from other sources (count: 23)

Approved Symbol	Approved Name	Source	Evidence[PMID]
HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)	Mapped by CNV
LIMA1	LIM domain and actin binding 1	Mapped by PBA pathway
COPB2	coatomer protein complex, subunit beta 2 (beta prime)	Mapped by PBA pathway
PPP1R12B	protein phosphatase 1, regulatory (inhibitor) subunit 12B	Mapped by LD-proxy; Mapped by literature SNP
GSN	gelsolin	Mapped by PBA pathway; Mapped by significant region
ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	Mapped by significant region	TAS[9230079]
TARS	threonyl-tRNA synthetase	Mapped by significant region
KLHL20	kelch-like 20 (Drosophila)	Mapped by significant region	TAS[10888605]
CTNNA3	catenin (cadherin-associated protein), alpha 3	Mapped by CNV
CORO2A	coronin, actin binding protein, 2A	Mapped by significant region
ARHGAP32	Rho GTPase activating protein 32	Mapped by significant region
CORO1B	coronin, actin binding protein, 1B	Mapped by significant region
CTNNAL1	catenin (cadherin-associated protein), alpha-like 1	Mapped by significant region
ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	Mapped by significant region	TAS[9230079]
ADAM17	ADAM metallopeptidase domain 17	Mapped by significant region	IDA[17010968]
PKNOX2	PBX/knotted 1 homeobox 2	Mapped by significant region
ACTL7B	actin-like 7B	Mapped by significant region	TAS[10373328]
IQGAP2	IQ motif containing GTPase activating protein 2	Mapped by CNV	TAS[8756646]
ZNF74	zinc finger protein 74	Mapped by CNV
FMN1	formin 1	Mapped by CNV; Mapped by significant region
FYB	FYN binding protein	Mapped by significant region	TAS[10747096]
ALDOA	aldolase A, fructose-bisphosphate	Mapped by CNV	IDA[9244396]
WASL	Wiskott-Aldrich syndrome-like	Mapped by CNV	TAS[9422512]