ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0008134
Name transcription factor binding
Type molecular function
No. of Genes in ADHDgene  44
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 44)

Literature-origin genes (count: 8)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
LMO4 LIM domain only 4 1p22.3 1(0/1/0) ISS
FOXP2 forkhead box P2 7q31 1(1/0/0) IBA
FOXP1 forkhead box P1 3p14.1 1(0/0/1) IBA
ARRB1 arrestin, beta 1 11q13 2(1/1/0) IPI[16325578]
HES1 hes family bHLH transcription factor 1 3q28-q29 1(1/0/0) NAS[17611704]
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 9q21.32 1(1/0/0) IDA[9751710]; IPI[8687460]
HES6 hes family bHLH transcription factor 6 2q37.3 1(0/1/0) NAS[17611704]
MEIS2 Meis homeobox 2 15q14 1(0/0/1) ISS

Genes from other sources Help (count: 36)

Approved Symbol Approved Name Source Evidence[PMID]
FOXD4 forkhead box D4 Mapped by CNV IBA
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 Mapped by significant region NAS[10698492]
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 Mapped by significant region IPI
HOXA7 homeobox A7 Mapped by significant region IPI[18973687]
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 Mapped by PBA pathway IPI[14701856]
UBE2I ubiquitin-conjugating enzyme E2I Mapped by significant region IPI[19744555]
SOX8 SRY (sex determining region Y)-box 8 Mapped by significant region IEA
KDM1A lysine (K)-specific demethylase 1A Mapped by LD-proxy IDA
STK36 serine/threonine kinase 36 Mapped by significant region IDA[10806483]
FOXE1 forkhead box E1 (thyroid transcription factor 2) Mapped by significant region IBA
FOXL1 forkhead box L1 Mapped by significant region IBA
MAPK9 mitogen-activated protein kinase 9 Mapped by CNV IDA[10376527]
FOXR1 forkhead box R1 Mapped by significant region IBA
SORBS3 sorbin and SH3 domain containing 3 Mapped by PBA pathway IEA
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 Mapped by PBA pathway ISS
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) Mapped by CNV ISS
NAAA N-acylethanolamine acid amidase Mapped by CNV IPI
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 Mapped by significant region NAS[17611704]
CREBBP CREB binding protein Mapped by significant region IPI[15509593]
DAXX death-domain associated protein Mapped by PBA pathway IDA[10698492]
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy IEA
KCTD1 potassium channel tetramerization domain containing 1 Mapped by significant region IPI[19115315]
HMGA1 high mobility group AT-hook 1 Mapped by PBA pathway IDA[10428834]
FOXG1 forkhead box G1 Mapped by significant region IBA
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) Mapped by significant region IEA
ZFPM1 zinc finger protein, FOG family member 1 Mapped by significant region IPI[12483298]
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A Mapped by significant region IPI[10849440]
FOXC2 forkhead box C2 (MFH-1, mesenchyme forkhead 1) Mapped by significant region IBA
FOXF1 forkhead box F1 Mapped by significant region IBA
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) Mapped by significant region IPI[16964248]
IGHMBP2 immunoglobulin mu binding protein 2 Mapped by CNV; Mapped by significant region IPI[19299493]
AIP aryl hydrocarbon receptor interacting protein Mapped by significant region TAS[9447995]
MED1 mediator complex subunit 1 Mapped by LD-proxy; Mapped by PBA pathway IPI[17641689]
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase Mapped by PBA pathway TAS[10976766]
KAT8 K(lysine) acetyltransferase 8 Mapped by CNV IDA[11742995]
GATA6 GATA binding protein 6 Mapped by significant region IPI[15016828]