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- Data Summary
GO Report
Basic Info
| ID | GO:0042734 |
|---|---|
| Name | presynaptic membrane |
| Type | Cellular Component |
| No. of Genes in ADHDgene | 15 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 15)
Literature-origin genes (count: 8)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| SYT1 | synaptotagmin I | 12cen-q21 | 4(2/2/0) | |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | 21q22 | 1(0/0/1) | |
| GRM7 | glutamate receptor, metabotropic 7 | 3p26-p25 | 1(1/0/0) | |
| SYP | synaptophysin | Xp11.23-p11.22 | 3(3/0/0) | |
| GRIK4 | glutamate receptor, ionotropic, kainate 4 | 11q | 1(0/1/0) | |
| NRXN1 | neurexin 1 | 2p16.3 | 1(0/1/0) | TAS[15797875] |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 16p13.2 | 3(1/2/0) | |
| SNPH | syntaphilin | 20p13 | 1(1/0/0) |
Genes from other sources (count: 7)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| UNC13C | unc-13 homolog C (C. elegans) | Mapped by CNV | |
| ACHE | acetylcholinesterase | Mapped by PBA pathway | |
| ADORA2A | adenosine A2a receptor | Mapped by CNV | |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | Mapped by significant region | |
| PICALM | phosphatidylinositol binding clathrin assembly protein | Mapped by significant region | |
| DENND1A | DENN/MADD domain containing 1A | Mapped by significant region | |
| FOSL1 | FOS-like antigen 1 | Mapped by significant region |