ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0042734
Name presynaptic membrane
Type cellular component
No. of Genes in ADHDgene  16
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 16)

Literature-origin genes (count: 8)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 16p13.2 4(1/3/0) IEA
NRXN1 neurexin 1 2p16.3 1(0/1/0) IEA; TAS[15797875]
SYP synaptophysin Xp11.23-p11.22 4(4/0/0) IEA
GRIK1 glutamate receptor, ionotropic, kainate 1 21q22 1(0/0/1) IEA
SNPH syntaphilin 20p13 1(1/0/0) IEA
GRM7 glutamate receptor, metabotropic 7 3p26-p25 3(2/1/0) IEA
GRIK4 glutamate receptor, ionotropic, kainate 4 11q23.3 1(0/1/0) IEA
SYT1 synaptotagmin I 12q21.2 4(2/2/0) IEA

Genes from other sources Help (count: 8)

Approved Symbol Approved Name Source Evidence[PMID]
PDE2A phosphodiesterase 2A, cGMP-stimulated Mapped by significant region ISS
DENND1A DENN/MADD domain containing 1A Mapped by significant region IEA
FOSL1 FOS-like antigen 1 Mapped by significant region IEA
PICK1 protein interacting with PRKCA 1 Mapped by Literature SNP IDA[11343649]
ADORA2A adenosine A2a receptor Mapped by CNV IEA
PICALM phosphatidylinositol binding clathrin assembly protein Mapped by significant region ISS
ACHE acetylcholinesterase (Yt blood group) Mapped by PBA pathway IBA
UNC13C unc-13 homolog C (C. elegans) Mapped by CNV IEA