ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0008017
Name	microtubule binding
Type	Molecular Function
No. of Genes in ADHDgene	32
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 32)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	4q21.3-q22	1(0/1/0)

Genes from other sources (count: 31)

Approved Symbol	Approved Name	Source	Evidence[PMID]
CEP57	centrosomal protein 57kDa	Mapped by significant region
ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	Mapped by PBA pathway	IDA[9857026]
PLK1	polo-like kinase 1	Mapped by significant region	IDA[12939256]
MAPRE2	microtubule-associated protein, RP/EB family, member 2	Mapped by significant region
TUBGCP6	tubulin, gamma complex associated protein 6	Mapped by PBA pathway	IDA[11694571]
HOOK3	hook homolog 3 (Drosophila)	Mapped by PBA pathway	IDA[11238449]
GABARAPL2	GABA(A) receptor-associated protein-like 2	Mapped by significant region	NAS[11414770]
KIF11	kinesin family member 11	Mapped by PBA pathway
KIF23	kinesin family member 23	Mapped by PBA pathway	IDA[11782313]
MAP6	microtubule-associated protein 6	Mapped by significant region
NUSAP1	nucleolar and spindle associated protein 1	Mapped by PBA pathway
CLASP1	cytoplasmic linker associated protein 1	Mapped by PBA pathway	IDA[11290329]; IMP[12837247]
REEP1	receptor accessory protein 1	Mapped by CNV
PRC1	protein regulator of cytokinesis 1	Mapped by PBA pathway
UXT	ubiquitously-expressed transcript	Mapped by PBA pathway	TAS[12762840]
PSRC1	proline/serine-rich coiled-coil 1	Mapped by CNV	ISS[12427559]
CCDC88A	coiled-coil domain containing 88A	Mapped by PBA pathway
MARK4	MAP/microtubule affinity-regulating kinase 4	Mapped by PBA pathway	IDA[14594945]
NDE1	nudE nuclear distribution gene E homolog 1 (A. nidulans)	Mapped by CNV; Mapped by significant region
MAP1S	microtubule-associated protein 1S	Mapped by PBA pathway	IDA[15528209]; TAS[12762840]
KATNB1	katanin p80 (WD repeat containing) subunit B 1	Mapped by PBA pathway	NAS[10751153]
CCDC87	coiled-coil domain containing 87	Mapped by significant region
TUBGCP5	tubulin, gamma complex associated protein 5	Mapped by PBA pathway; Mapped by significant region	IDA[11694571]
MAPT	microtubule-associated protein tau	Mapped by LD-proxy; Mapped by PBA pathway	IDA[1918161]
CRYAB	crystallin, alpha B	Mapped by significant region
CDK5RAP2	CDK5 regulatory subunit associated protein 2	Mapped by significant region	IDA[14654843]
CCDC88B	coiled-coil domain containing 88B	Mapped by significant region
JAKMIP3	Janus kinase and microtubule interacting protein 3	Mapped by CNV
APC	adenomatous polyposis coli	Mapped by LD-proxy; Mapped by PBA pathway	IDA[16188939]
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	Mapped by PBA pathway	ISS[10729324]
TPPP	tubulin polymerization promoting protein	Mapped by PBA pathway