ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0006260
Name	DNA replication
Type	Biological Process
No. of Genes in ADHDgene	27
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 27)

Literature-origin genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
FHIT	fragile histidine triad gene	3p14.2	1(0/0/1)
ADRA2A	adrenergic, alpha-2A-, receptor	10q24-q26	12(4/8/0)

Genes from other sources (count: 25)

Approved Symbol	Approved Name	Source	Evidence[PMID]
INO80E	INO80 complex subunit E	Mapped by CNV
IGHMBP2	immunoglobulin mu binding protein 2	Mapped by CNV; Mapped by significant region	TAS[8493094]
CDT1	chromatin licensing and DNA replication factor 1	Mapped by significant region
MCM9	minichromosome maintenance complex component 9	Mapped by significant region
ACHE	acetylcholinesterase	Mapped by PBA pathway	TAS[11283752]
POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)	Mapped by significant region	NAS[8223465]
TBRG1	transforming growth factor beta regulator 1	Mapped by significant region	IMP[17110379]
POLE	polymerase (DNA directed), epsilon	Mapped by CNV	IMP[16762037]
CHEK1	CHK1 checkpoint homolog (S. pombe)	Mapped by significant region
KCTD13	potassium channel tetramerisation domain containing 13	Mapped by CNV	ISS[15726626]
CTGF	connective tissue growth factor	Mapped by significant region
CCDC88A	coiled-coil domain containing 88A	Mapped by PBA pathway
RBM14	RNA binding motif protein 14	Mapped by significant region	NAS[11443112]
RAD9A	RAD9 homolog A (S. pombe)	Mapped by significant region
SSRP1	structure specific recognition protein 1	Mapped by significant region
MED1	mediator complex subunit 1	Mapped by LD-proxy; Mapped by PBA pathway
POLE3	polymerase (DNA directed), epsilon 3 (p17 subunit)	Mapped by significant region	TAS[10801849]
NOL8	nucleolar protein 8	Mapped by significant region	IMP[14660641]
POLD4	polymerase (DNA-directed), delta 4	Mapped by significant region	TAS[10751307]
RRM2	ribonucleotide reductase M2	Mapped by significant region
CDC45	cell division cycle 45 homolog (S. cerevisiae)	Mapped by CNV
RAD1	RAD1 homolog (S. pombe)	Mapped by significant region
NCOA6	nuclear receptor coactivator 6	Mapped by PBA pathway	NAS[11443112]
NT5M	5',3'-nucleotidase, mitochondrial	Mapped by significant region	TAS[10899995]
FEN1	flap structure-specific endonuclease 1	Mapped by LD-proxy; Mapped by literature SNP; Mapped by significant region	NAS[15504738]