ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0019233
Name sensory perception of pain
Type biological process
No. of Genes in ADHDgene  18
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 18)

Literature-origin genes (count: 8)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 16p13.2 4(1/3/0) IEA
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 20q13.33 7(4/3/0) ISS
CNR1 cannabinoid receptor 1 (brain) 6q14-q15 1(1/0/0) IEA
OPRM1 opioid receptor, mu 1 6q24-q25 1(1/0/0) ISS
ADRB1 adrenoceptor beta 1 10q25.3 2(0/2/0) IEA
GRM1 glutamate receptor, metabotropic 1 6q24 1(1/0/0) IEA
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 13q14-q21 13(7/6/0) IEA
NGF nerve growth factor (beta polypeptide) 1p13.1 2(2/0/0) IEA

Genes from other sources Help (count: 10)

Approved Symbol Approved Name Source Evidence[PMID]
MAPK3 mitogen-activated protein kinase 3 Mapped by CNV IEA
NMU neuromedin U Mapped by LD-proxy IEA
SCN3B sodium channel, voltage-gated, type III, beta subunit Mapped by significant region IEA
DLG2 discs, large homolog 2 (Drosophila) Mapped by significant region IEA
EDNRA endothelin receptor type A Mapped by PBA pathway IEA
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) Mapped by significant region IEA
NDN necdin, melanoma antigen (MAGE) family member Mapped by CNV; Mapped by significant region IEA
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit Mapped by significant region; Mapped by PBA pathway IEA
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy IEA
FAM134B family with sequence similarity 134, member B Mapped by significant region IMP[19838196]