ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0032403
Name	protein complex binding
Type	Molecular Function
No. of Genes in ADHDgene	27
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 27)

Literature-origin genes (count: 6)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
ARRB2	arrestin, beta 2	17p13	1(1/0/0)
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	5p15.3	68(42/25/1)
SYP	synaptophysin	Xp11.23-p11.22	3(3/0/0)
TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	8q13.3	1(0/0/1)
HTR2A	5-hydroxytryptamine (serotonin) receptor 2A	13q14-q21	12(6/6/0)
DNM1	dynamin 1	9q34	1(0/0/1)

Genes from other sources (count: 21)

Approved Symbol	Approved Name	Source	Evidence[PMID]
FLCN	folliculin	Mapped by significant region	IDA[17028174]
KAT5	K(lysine) acetyltransferase 5	Mapped by significant region
FYB	FYN binding protein	Mapped by significant region
UQCRC2	ubiquinol-cytochrome c reductase core protein II	Mapped by CNV; Mapped by significant region
PDCL	phosducin-like	Mapped by significant region
ATM	ataxia telangiectasia mutated	Mapped by CNV; Mapped by significant region	IDA[15790808]
TMED10	transmembrane emp24-like trafficking protein 10 (yeast)	Mapped by PBA pathway
RPTOR	regulatory associated protein of MTOR, complex 1	Mapped by LD-proxy	IPI[19211835]
SREBF1	sterol regulatory element binding transcription factor 1	Mapped by significant region
STRN3	striatin, calmodulin binding protein 3	Mapped by significant region	IDA[18782753]
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	Mapped by PBA pathway
CCND1	cyclin D1	Mapped by significant region
CAV3	caveolin 3	Mapped by LD-proxy; Mapped by literature SNP	IDA[10988290]
CTSL2	cathepsin L2	Mapped by significant region
SH2B3	SH2B adaptor protein 3	Mapped by LD-proxy
UFD1L	ubiquitin fusion degradation 1 like (yeast)	Mapped by CNV
RNF40	ring finger protein 40	Mapped by CNV
CDK5RAP2	CDK5 regulatory subunit associated protein 2	Mapped by significant region
PTCH1	patched 1	Mapped by significant region
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	Mapped by significant region
ERCC8	excision repair cross-complementing rodent repair deficiency, complementation group 8	Mapped by CNV	IDA[16916636]