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- Data Summary
GO Report
Basic Info
| ID | GO:0004435 |
|---|---|
| Name | phosphatidylinositol phospholipase C activity |
| Type | Molecular Function |
| No. of Genes in ADHDgene | 20 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 20)
Literature-origin genes (count: 3)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| HTR2C | 5-hydroxytryptamine (serotonin) receptor 2C | Xq24 | 5(2/3/0) | IDA[12970106] |
| HTR2A | 5-hydroxytryptamine (serotonin) receptor 2A | 13q14-q21 | 12(6/6/0) | IMP[16517693] |
| PLCL1 | phospholipase C-like 1 | 2q33 | 1(0/0/1) |
Genes from other sources (count: 17)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| PLCB2 | phospholipase C, beta 2 | Mapped by PBA pathway | |
| CASR | calcium-sensing receptor | Mapped by PBA pathway | TAS[7874174] |
| CCKBR | cholecystokinin B receptor | Mapped by CNV; Mapped by PBA pathway | TAS[7681836] |
| CHRM5 | cholinergic receptor, muscarinic 5 | Mapped by CNV; Mapped by PBA pathway | TAS[1905013] |
| PLCD1 | phospholipase C, delta 1 | Mapped by PBA pathway | |
| C3AR1 | complement component 3a receptor 1 | Mapped by PBA pathway | TAS[8765043] |
| PLCD4 | phospholipase C, delta 4 | Mapped by significant region | |
| F2RL2 | coagulation factor II (thrombin) receptor-like 2 | Mapped by PBA pathway | TAS[9087410] |
| CHRM3 | cholinergic receptor, muscarinic 3 | Mapped by CNV; Mapped by PBA pathway | TAS[1905013] |
| BDKRB2 | bradykinin receptor B2 | Mapped by PBA pathway | TAS[8302267] |
| EDNRA | endothelin receptor type A | Mapped by PBA pathway | TAS[8702836] |
| PLCH1 | phospholipase C, eta 1 | Mapped by PBA pathway | |
| CCR5 | chemokine (C-C motif) receptor 5 | Mapped by PBA pathway | TAS[8663314] |
| CHRM1 | cholinergic receptor, muscarinic 1 | Mapped by PBA pathway; Mapped by significant region | TAS[9614217] |
| PLCE1 | phospholipase C, epsilon 1 | Mapped by PBA pathway | IDA[11022047] |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | Mapped by significant region | |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | Mapped by significant region | IDA[12181444] |