ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0004435
Name phosphatidylinositol phospholipase C activity
Type molecular function
No. of Genes in ADHDgene  20
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 20)

Literature-origin genes (count: 3)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
PLCL1 phospholipase C-like 1 2q33 1(0/0/1) IEA
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Xq23 5(2/3/0) IDA[12970106]
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 13q14-q21 13(7/6/0) IMP[16517693]

Genes from other sources Help (count: 17)

Approved Symbol Approved Name Source Evidence[PMID]
CHRM1 cholinergic receptor, muscarinic 1 Mapped by significant region; Mapped by PBA pathway TAS[9614217]
BDKRB2 bradykinin receptor B2 Mapped by PBA pathway TAS[8302267]
CASR calcium-sensing receptor Mapped by PBA pathway TAS[7874174]
PLCD4 phospholipase C, delta 4 Mapped by significant region IEA
PLCD1 phospholipase C, delta 1 Mapped by PBA pathway IEA
PLCH1 phospholipase C, eta 1 Mapped by PBA pathway IEA
EDNRA endothelin receptor type A Mapped by PBA pathway TAS[8702836]
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) Mapped by significant region IDA[12181444]
PLCE1 phospholipase C, epsilon 1 Mapped by PBA pathway IDA[11022047]
CCKBR cholecystokinin B receptor Mapped by CNV; Mapped by PBA pathway TAS[7681836]
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) Mapped by significant region IEA
C3AR1 complement component 3a receptor 1 Mapped by PBA pathway TAS[8765043]
CHRM5 cholinergic receptor, muscarinic 5 Mapped by CNV; Mapped by PBA pathway TAS[1905013]
CHRM3 cholinergic receptor, muscarinic 3 Mapped by CNV; Mapped by PBA pathway TAS[1905013]
PLCB2 phospholipase C, beta 2 Mapped by PBA pathway IEA
F2RL2 coagulation factor II (thrombin) receptor-like 2 Mapped by PBA pathway TAS[9087410]
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) Mapped by PBA pathway TAS[8663314]