ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0008286
Name	insulin receptor signaling pathway
Type	Biological Process
No. of Genes in ADHDgene	32
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 32)

Literature-origin genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
BAIAP2	BAI1-associated protein 2	17q25	1(1/0/0)	TAS[10343108]
FGF10	fibroblast growth factor 10	5p13-p12	1(0/1/0)
PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	7q35-q36	1(0/0/1)

Genes from other sources (count: 29)

Approved Symbol	Approved Name	Source	Evidence[PMID]
FGF4	fibroblast growth factor 4	Mapped by significant region
INS	insulin	Mapped by literature SNP
MAPK3	mitogen-activated protein kinase 3	Mapped by CNV
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	Mapped by CNV
BCAR1	breast cancer anti-estrogen resistance 1	Mapped by significant region
TSC1	tuberous sclerosis 1	Mapped by PBA pathway
TCIRG1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	Mapped by significant region
ATP6V1C2	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2	Mapped by significant region
PIK3C3	phosphoinositide-3-kinase, class 3	Mapped by significant region
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	Mapped by significant region
RPTOR	regulatory associated protein of MTOR, complex 1	Mapped by LD-proxy
EEF2K	eukaryotic elongation factor-2 kinase	Mapped by CNV; Mapped by significant region
ATP6V1F	ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F	Mapped by LD-proxy
MAPK1	mitogen-activated protein kinase 1	Mapped by LD-proxy
SLC2A8	solute carrier family 2 (facilitated glucose transporter), member 8	Mapped by significant region
FGF3	fibroblast growth factor 3	Mapped by significant region
GRB10	growth factor receptor-bound protein 10	Mapped by LD-proxy
PRKAG3	protein kinase, AMP-activated, gamma 3 non-catalytic subunit	Mapped by significant region
FGF9	fibroblast growth factor 9 (glia-activating factor)	Mapped by significant region
IGF2	insulin-like growth factor 2 (somatomedin A)	Mapped by LD-proxy; Mapped by literature SNP	TAS[1845984]
SREBF1	sterol regulatory element binding transcription factor 1	Mapped by significant region
FGF19	fibroblast growth factor 19	Mapped by significant region
ATP6V1G1	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1	Mapped by significant region
ATP6V0A2	ATPase, H+ transporting, lysosomal V0 subunit a2	Mapped by CNV
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	Mapped by significant region	IPI[8276809]
SIK2	salt-inducible kinase 2	Mapped by significant region
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	Mapped by significant region	IDA[16456100]
ATP6V0D2	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2	Mapped by CNV
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	Mapped by significant region