ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0008286
Name insulin receptor signaling pathway
Type biological process
No. of Genes in ADHDgene  37
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 37)

Literature-origin genes (count: 3)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
FGF10 fibroblast growth factor 10 5p13-p12 1(0/1/0) TAS
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 7q35-q36 1(0/0/1) TAS
BAIAP2 BAI1-associated protein 2 17q25 1(1/0/0) TAS[10343108]

Genes from other sources Help (count: 34)

Approved Symbol Approved Name Source Evidence[PMID]
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Mapped by significant region IPI[8276809]; TAS
FGF9 fibroblast growth factor 9 Mapped by significant region TAS
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit Mapped by significant region TAS
SIK2 salt-inducible kinase 2 Mapped by significant region IEA
PDPK1 3-phosphoinositide dependent protein kinase-1 Mapped by significant region TAS
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 Mapped by significant region IEA
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 Mapped by significant region TAS
EEF2K eukaryotic elongation factor-2 kinase Mapped by CNV; Mapped by significant region TAS
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F Mapped by LD-proxy TAS
FGF3 fibroblast growth factor 3 Mapped by significant region TAS
BCAR1 breast cancer anti-estrogen resistance 1 Mapped by significant region ISS
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) Mapped by significant region TAS
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 Mapped by CNV TAS
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 Mapped by significant region TAS
FGF19 fibroblast growth factor 19 Mapped by significant region TAS
INS insulin Mapped by Literature SNP TAS
IGF2 insulin-like growth factor 2 (somatomedin A) Mapped by LD-proxy TAS[1845984]
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit Mapped by CNV TAS
FGF4 fibroblast growth factor 4 Mapped by significant region TAS
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy TAS
TSC2 tuberous sclerosis 2 Mapped by significant region TAS
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c Mapped by significant region TAS
RPTOR regulatory associated protein of MTOR, complex 1 Mapped by LD-proxy TAS
STK11 serine/threonine kinase 11 Mapped by CNV TAS
TLR9 toll-like receptor 9 Mapped by LD-proxy TAS
GRB10 growth factor receptor-bound protein 10 Mapped by LD-proxy ISS; TAS
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 Mapped by significant region TAS
SREBF1 sterol regulatory element binding transcription factor 1 Mapped by significant region IEA
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit Mapped by significant region TAS
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 Mapped by significant region TAS
TSC1 tuberous sclerosis 1 Mapped by PBA pathway TAS
MAPK3 mitogen-activated protein kinase 3 Mapped by CNV TAS
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 Mapped by significant region TAS
FOXC2 forkhead box C2 (MFH-1, mesenchyme forkhead 1) Mapped by significant region IDA[16456100]