ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0008543
Name	fibroblast growth factor receptor signaling pathway
Type	Biological Process
No. of Genes in ADHDgene	26
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 26)

Literature-origin genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
GSK3B	glycogen synthase kinase 3 beta	3q13.3	1(1/0/0)
ADRBK1	adrenergic, beta, receptor kinase 1	11q13	1(0/1/0)
FGF10	fibroblast growth factor 10	5p13-p12	1(0/1/0)

Genes from other sources (count: 23)

Approved Symbol	Approved Name	Source	Evidence[PMID]
FGF4	fibroblast growth factor 4	Mapped by significant region	IGI[8663044]
SHOC2	soc-2 suppressor of clear homolog (C. elegans)	Mapped by LD-proxy	NAS[9618511]
CEP57	centrosomal protein 57kDa	Mapped by significant region	IPI[12717444]
FIBP	fibroblast growth factor (acidic) intracellular binding protein	Mapped by significant region	TAS[9806903]
MAPK3	mitogen-activated protein kinase 3	Mapped by CNV
PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta	Mapped by CNV
ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	Mapped by LD-proxy; Mapped by literature SNP
ITPR1	inositol 1,4,5-trisphosphate receptor, type 1	Mapped by CNV
BAD	BCL2-associated agonist of cell death	Mapped by significant region
FGF3	fibroblast growth factor 3	Mapped by significant region	IGI[8663044]
RICTOR	RPTOR independent companion of MTOR, complex 2	Mapped by significant region
MAPK1	mitogen-activated protein kinase 1	Mapped by LD-proxy
FGF9	fibroblast growth factor 9 (glia-activating factor)	Mapped by significant region	IGI[8663044]
RAB14	RAB14, member RAS oncogene family	Mapped by PBA pathway; Mapped by significant region
FGF19	fibroblast growth factor 19	Mapped by significant region	IGI[18187602]; IPI[10525310]
RPS6KB2	ribosomal protein S6 kinase, 70kDa, polypeptide 2	Mapped by significant region
UBB	ubiquitin B	Mapped by significant region
CTGF	connective tissue growth factor	Mapped by significant region
UBC	ubiquitin C	Mapped by CNV
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	Mapped by significant region
ADCY4	adenylate cyclase 4	Mapped by significant region
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	Mapped by significant region
MAPKAP1	mitogen-activated protein kinase associated protein 1	Mapped by significant region