ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0031145
Name	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
Type	Biological Process
No. of Genes in ADHDgene	14
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 14)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	11p11.2	1(0/0/1)

Genes from other sources (count: 13)

Approved Symbol	Approved Name	Source	Evidence[PMID]
PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)	Mapped by significant region
PLK1	polo-like kinase 1	Mapped by significant region
SKP2	S-phase kinase-associated protein 2 (p45)	Mapped by significant region
UBB	ubiquitin B	Mapped by significant region
PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	Mapped by significant region
PSMA8	proteasome (prosome, macropain) subunit, alpha type, 8	Mapped by significant region
PSMD5	proteasome (prosome, macropain) 26S subunit, non-ATPase, 5	Mapped by significant region
PSMB7	proteasome (prosome, macropain) subunit, beta type, 7	Mapped by significant region
PTTG1	pituitary tumor-transforming 1	Mapped by significant region
UBC	ubiquitin C	Mapped by CNV
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	Mapped by significant region
ANAPC4	anaphase promoting complex subunit 4	Mapped by CNV
CDC26	cell division cycle 26 homolog (S. cerevisiae)	Mapped by significant region