ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0006950
Name	response to stress
Type	Biological Process
No. of Genes in ADHDgene	30
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 30)

Literature-origin genes (count: 4)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
TPH2	tryptophan hydroxylase 2	12q15	10(7/3/0)
CNR1	cannabinoid receptor 1 (brain)	6q14-q15	1(1/0/0)
ADRA1A	adrenergic, alpha-1A-, receptor	8p21.2	3(2/1/0)
HTR2A	5-hydroxytryptamine (serotonin) receptor 2A	13q14-q21	12(6/6/0)

Genes from other sources (count: 26)

Approved Symbol	Approved Name	Source	Evidence[PMID]
IGFBP2	insulin-like growth factor binding protein 2, 36kDa	Mapped by significant region
C5	complement component 5	Mapped by significant region	TAS[9590258]
RTN3	reticulon 3	Mapped by significant region
ERN2	endoplasmic reticulum to nucleus signaling 2	Mapped by significant region
ERP44	endoplasmic reticulum protein 44	Mapped by significant region	IDA[11847130]
NMU	neuromedin U	Mapped by LD-proxy
STIP1	stress-induced-phosphoprotein 1	Mapped by significant region	TAS[1569099]
SYT10	synaptotagmin X	Mapped by CNV
FLCN	folliculin	Mapped by significant region	IMP[17028174]
MAPK9	mitogen-activated protein kinase 9	Mapped by CNV	TAS[7969172]
SGK1	serum/glucocorticoid regulated kinase 1	Mapped by significant region	TAS[9114008]
MAPK1	mitogen-activated protein kinase 1	Mapped by LD-proxy	TAS[10958679]
MAP4K2	mitogen-activated protein kinase kinase kinase kinase 2	Mapped by significant region	TAS[8643544]
HSF2	heat shock transcription factor 2	Mapped by significant region
HYOU1	hypoxia up-regulated 1	Mapped by significant region	TAS[9020069]
SQSTM1	sequestosome 1	Mapped by CNV	TAS[12857745]
TAOK2	TAO kinase 2	Mapped by CNV	IDA[10660600]
CA2	carbonic anhydrase II	Mapped by CNV
SMG1	smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)	Mapped by significant region	IDA[15175154]
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	Mapped by significant region
TCAP	titin-cap (telethonin)	Mapped by LD-proxy; Mapped by literature SNP	TAS[17921333]
GADD45G	growth arrest and DNA-damage-inducible, gamma	Mapped by significant region	TAS[9827804]
MAPKAP1	mitogen-activated protein kinase associated protein 1	Mapped by significant region
ATF6	activating transcription factor 6	Mapped by CNV	TAS[10866666]
PRKRIR	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)	Mapped by significant region	TAS[9447982]
CHORDC1	cysteine and histidine-rich domain (CHORD) containing 1	Mapped by significant region