ADHDgene Database

Gene Report

Basic Info

Approved Symbol	IGFBP2
Previous Symbol	IBP2
Approved Name	insulin-like growth factor binding protein 2, 36kDa
Previous Name	insulin-like growth factor binding protein 2 (36kD)
Location	2q33-q34
Position	chr2:217497551-217529159, +
External Links	HGNC: 5471 Entrez Gene: 3485 Ensembl: ENSG00000115457 UCSC: uc010zjt.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
2q35	chr2:215300000-221500000	1 (1/0/0)

Gene related GO terms (count: 22)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005615	extracellular space	Cellular Component	IDA[15694994]	126
GO:0006950	response to stress	Biological Process		30
GO:0005515	protein binding	Molecular Function	IPI[19095771]	910
GO:0005576	extracellular region	Cellular Component		240
GO:0007568	aging	Biological Process		29
GO:0007584	response to nutrient	Biological Process		15
GO:0007165	signal transduction	Biological Process		171
GO:0007565	female pregnancy	Biological Process		14
GO:0001558	regulation of cell growth	Biological Process		11
GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	Biological Process	IC[19081843]	1
GO:0042493	response to drug	Biological Process		68
GO:0042104	positive regulation of activated T cell proliferation	Biological Process	IDA[15694994]	6
GO:0032870	cellular response to hormone stimulus	Biological Process		7
GO:0051384	response to glucocorticoid stimulus	Biological Process		17
GO:0031410	cytoplasmic vesicle	Cellular Component		20
GO:0016324	apical plasma membrane	Cellular Component		51
GO:0010226	response to lithium ion	Biological Process		2
GO:0009612	response to mechanical stimulus	Biological Process		9
GO:0032526	response to retinoic acid	Biological Process		7
GO:0032355	response to estradiol stimulus	Biological Process		18
GO:0031995	insulin-like growth factor II binding	Molecular Function		1
GO:0031994	insulin-like growth factor I binding	Molecular Function	IDA[19081843]	2

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with IGFBP2 (count: 7)

Gene Symbol	Pathway Count	Pathway List
APOA1	6	extracellular space; protein binding; extracellular region; response to nutrient; response to drug; cytoplasmic vesicle;
GHR	6	extracellular space; protein binding; extracellular region; cellular response to hormone stimulus; response to glucocorticoid stimulus; response to estradiol stimulus;
IL6	6	extracellular space; extracellular region; aging; response to drug; response to glucocorticoid stimulus; response to mechanical stimulus;
NGF	5	extracellular space; extracellular region; response to drug; response to glucocorticoid stimulus; response to mechanical stimulus;
SCGB1A1	5	extracellular space; signal transduction; female pregnancy; response to drug; response to glucocorticoid stimulus;
DUSP1	5	protein binding; cellular response to hormone stimulus; response to glucocorticoid stimulus; response to retinoic acid; response to estradiol stimulus;
IGFBP5	5	protein binding; extracellular region; signal transduction; regulation of cell growth; insulin-like growth factor I binding;

Genes shared at least 2 KEGG pathways with IGFBP2 (count: 0)

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Region: chr2:217497551..217529159 View in gBrowse