ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	IGFBP5
Approved Name	insulin-like growth factor binding protein 5
Location	2q33-q36
Position	chr2:217536828-217560272, -
External Links	HGNC: 5474 Entrez Gene: 3488 Ensembl: ENSG00000115461 UCSC: uc002vgj.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
2q35	chr2:215300000-221500000	1 (1/0/0)

Gene related GO terms (count: 27)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 27)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0001968	fibronectin binding	Molecular Function		3
GO:0001649	osteoblast differentiation	Biological Process		9
GO:0001558	regulation of cell growth	Biological Process		11
GO:0042593	glucose homeostasis	Biological Process		18
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	Biological Process		1
GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway	Biological Process	IDA[10766744]	3
GO:0044342	type B pancreatic cell proliferation	Biological Process		2
GO:0030336	negative regulation of cell migration	Biological Process	IDA[15700281]	13
GO:0031069	hair follicle morphogenesis	Biological Process		4
GO:0031994	insulin-like growth factor I binding	Molecular Function	IPI[10766744]	2
GO:0035556	intracellular signal transduction	Biological Process		44
GO:0010906	regulation of glucose metabolic process	Biological Process		2
GO:0014912	negative regulation of smooth muscle cell migration	Biological Process	IDA[10766744]	2
GO:0016942	insulin-like growth factor binding protein complex	Cellular Component	IC[10766744]	1
GO:0017148	negative regulation of translation	Biological Process	IDA[15700281]	5
GO:0005515	protein binding	Molecular Function	IPI[15700281]	910
GO:0005576	extracellular region	Cellular Component	NAS[14718574]	240
GO:0006006	glucose metabolic process	Biological Process		19
GO:0007165	signal transduction	Biological Process	NAS[7525452]	171
GO:0060056	mammary gland involution	Biological Process		3
GO:0051897	positive regulation of protein kinase B signaling cascade	Biological Process		17
GO:0071407	cellular response to organic cyclic compound	Biological Process	IDA[7559606]	4
GO:0071320	cellular response to cAMP	Biological Process	IDA[7559606]	5
GO:0048630	skeletal muscle tissue growth	Biological Process		1
GO:0045668	negative regulation of osteoblast differentiation	Biological Process		6
GO:0051146	striated muscle cell differentiation	Biological Process		2
GO:0048662	negative regulation of smooth muscle cell proliferation	Biological Process	IDA[10766744]	7

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with IGFBP5 (count: 2)

Gene Symbol	Pathway Count	Pathway List
IGFBP2	5	regulation of cell growth; insulin-like growth factor I binding; protein binding; extracellular region; signal transduction;
INS	5	glucose homeostasis; protein binding; extracellular region; glucose metabolic process; positive regulation of protein kinase B signaling cascade;

Genes shared at least 2 KEGG pathways with IGFBP5 (count: 0)

View in gBrowse

Region: chr2:217536828..217560272 View in gBrowse