ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	SCGB1A1
Previous Symbol	UGB
Symbol Alias	CC10, CCSP, CC16
Approved Name	secretoglobin, family 1A, member 1 (uteroglobin)
Previous Name	uteroglobin
Name Alias	Uteroglobin (Clara-cell specific 10-kD protein)
Location	11q11-qter
Position	chr11:62172575-62190678, +
External Links	HGNC: 12523 Entrez Gene: 7356 Ensembl: ENSG00000149021 UCSC: uc001ntj.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 24)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 24)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0051384	response to glucocorticoid stimulus	Biological Process		17
GO:0071774	response to fibroblast growth factor stimulus	Biological Process		1
GO:0043488	regulation of mRNA stability	Biological Process		2
GO:0050727	regulation of inflammatory response	Biological Process		8
GO:0032713	negative regulation of interleukin-4 production	Biological Process		1
GO:0032714	negative regulation of interleukin-5 production	Biological Process		1
GO:0032689	negative regulation of interferon-gamma production	Biological Process		4
GO:0032696	negative regulation of interleukin-13 production	Biological Process		1
GO:0042130	negative regulation of T cell proliferation	Biological Process		3
GO:0042493	response to drug	Biological Process		68
GO:0034021	response to silicon dioxide	Biological Process		1
GO:0034097	response to cytokine stimulus	Biological Process		9
GO:0007565	female pregnancy	Biological Process	NAS[10587371]	14
GO:0007165	signal transduction	Biological Process	NAS[10587371]	171
GO:0009410	response to xenobiotic stimulus	Biological Process		1
GO:0007566	embryo implantation	Biological Process	TAS[10587371]	3
GO:0019834	phospholipase A2 inhibitor activity	Molecular Function		1
GO:0010193	response to ozone	Biological Process		3
GO:0032496	response to lipopolysaccharide	Biological Process		22
GO:0030141	secretory granule	Cellular Component		17
GO:0005615	extracellular space	Cellular Component		126
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process		78
GO:0005791	rough endoplasmic reticulum	Cellular Component		7
GO:0005635	nuclear envelope	Cellular Component		19

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SCGB1A1 (count: 2)

Gene Symbol	Pathway Count	Pathway List
IGFBP2	5	response to glucocorticoid stimulus; response to drug; female pregnancy; signal transduction; extracellular space;
NGF	5	response to glucocorticoid stimulus; response to drug; response to ozone; response to lipopolysaccharide; extracellular space;

Genes shared at least 2 KEGG pathways with SCGB1A1 (count: 0)

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Region: chr11:62172575..62190678 View in gBrowse