ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0046983
Name	protein dimerization activity
Type	Molecular Function
No. of Genes in ADHDgene	26
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 26)

Literature-origin genes (count: 5)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
CLOCK	clock homolog (mouse)	4q12	2(2/0/0)
ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	2p25	1(0/1/0)
HES6	hairy and enhancer of split 6 (Drosophila)	2q37.3	1(0/1/0)
NEUROD6	neurogenic differentiation 6	7p15.1	1(0/1/0)
NPAS3	neuronal PAS domain protein 3	14q12-q13	1(1/0/0)

Genes from other sources (count: 21)

Approved Symbol	Approved Name	Source	Evidence[PMID]
ATM	ataxia telangiectasia mutated	Mapped by CNV; Mapped by significant region	IDA[15790808]
SREBF1	sterol regulatory element binding transcription factor 1	Mapped by significant region
POU2F3	POU class 2 homeobox 3	Mapped by significant region
MYO7A	myosin VIIA	Mapped by significant region	RCA[8622919]
SCAND3	SCAN domain containing 3	Mapped by LD-proxy
TCF21	transcription factor 21	Mapped by CNV; Mapped by significant region
TAL2	T-cell acute lymphocytic leukemia 2	Mapped by significant region
WWOX	WW domain containing oxidoreductase	Mapped by significant region	TAS[10786676]
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	Mapped by CNV	IDA[12072434]
TBX1	T-box 1	Mapped by CNV	TAS[17273972]
EBF1	early B-cell factor 1	Mapped by significant region
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	Mapped by LD-proxy	NAS[12000754]
NPAS2	neuronal PAS domain protein 2	Mapped by CNV
SLC4A11	solute carrier family 4, sodium borate transporter, member 11	Mapped by CNV
HEY2	hairy/enhancer-of-split related with YRPW motif 2	Mapped by significant region
PRDX5	peroxiredoxin 5	Mapped by significant region	IDA[15046979]
OLIG3	oligodendrocyte transcription factor 3	Mapped by significant region
GPR139	G protein-coupled receptor 139	Mapped by significant region
NLGN1	neuroligin 1	Mapped by CNV
PRKRIR	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)	Mapped by significant region
SPEF2	sperm flagellar 2	Mapped by significant region