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- Data Summary
GO Report
Basic Info
| ID | GO:0051897 |
|---|---|
| Name | positive regulation of protein kinase B signaling cascade |
| Type | Biological Process |
| No. of Genes in ADHDgene | 17 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 17)
Literature-origin genes (count: 2)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| ARRB2 | arrestin, beta 2 | 17p13 | 1(1/0/0) | |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 11p11.2 | 1(0/1/0) | IMP[18936167] |
Genes from other sources (count: 15)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | Mapped by significant region | |
| IL6 | interleukin 6 (interferon, beta 2) | Mapped by significant region | |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) | Mapped by CNV | IDA[18612547] |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) | Mapped by significant region | ISS[18292087] |
| VEGFB | vascular endothelial growth factor B | Mapped by significant region | IDA[18259607] |
| F10 | coagulation factor X | Mapped by CNV | IDA[18612547] |
| CCL19 | chemokine (C-C motif) ligand 19 | Mapped by LD-proxy | IDA[15778365] |
| ILK | integrin-linked kinase | Mapped by CNV | |
| TGFBR1 | transforming growth factor, beta receptor 1 | Mapped by significant region | IDA[18625725] |
| NOX4 | NADPH oxidase 4 | Mapped by significant region | |
| IGFBP5 | insulin-like growth factor binding protein 5 | Mapped by significant region | |
| INS | insulin | Mapped by literature SNP | IDA[11500939] |
| PIK3CG | phosphoinositide-3-kinase, catalytic, gamma polypeptide | Mapped by CNV | IDA[12507995] |
| ADAM8 | ADAM metallopeptidase domain 8 | Mapped by CNV; Mapped by LD-proxy | |
| IGF2 | insulin-like growth factor 2 (somatomedin A) | Mapped by LD-proxy; Mapped by literature SNP | IDA[11500939] |