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- Data Summary
GO Report
Basic Info
| ID | GO:0005506 |
|---|---|
| Name | iron ion binding |
| Type | Molecular Function |
| No. of Genes in ADHDgene | 20 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 20)
Literature-origin genes (count: 6)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| TPH2 | tryptophan hydroxylase 2 | 12q15 | 10(7/3/0) | |
| NOS1 | nitric oxide synthase 1 (neuronal) | 12q14-qter | 1(1/0/0) | |
| TPH1 | tryptophan hydroxylase 1 | 11p15.3-p14 | 6(2/4/0) | |
| FADS2 | fatty acid desaturase 2 | 11q12.2 | 3(3/0/0) | |
| TDO2 | tryptophan 2,3-dioxygenase | 4q31-q32 | 1(1/0/0) | |
| FADS1 | fatty acid desaturase 1 | 11q12-q13.1 | 3(1/2/0) |
Genes from other sources (count: 14)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 | Mapped by CNV | |
| CYCS | cytochrome c, somatic | Mapped by CNV; Mapped by significant region | |
| P4HA3 | prolyl 4-hydroxylase, alpha polypeptide III | Mapped by significant region | |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein | Mapped by significant region | |
| FDX1 | ferredoxin 1 | Mapped by significant region | TAS[2969697] |
| FTH1 | ferritin, heavy polypeptide 1 | Mapped by significant region | TAS[3020541] |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 | Mapped by significant region | |
| HBG2 | hemoglobin, gamma G | Mapped by CNV | |
| EGLN3 | egl nine homolog 3 (C. elegans) | Mapped by LD-proxy; Mapped by literature SNP | |
| FA2H | fatty acid 2-hydroxylase | Mapped by significant region | |
| PPEF2 | protein phosphatase, EF-hand calcium binding domain 2 | Mapped by CNV | |
| SC5DL | sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like | Mapped by significant region | |
| PHF2 | PHD finger protein 2 | Mapped by significant region | |
| FADS3 | fatty acid desaturase 3 | Mapped by LD-proxy; Mapped by significant region |