ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0005125
Name	cytokine activity
Type	Molecular Function
No. of Genes in ADHDgene	19
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 19)

Literature-origin genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
VEGFA	vascular endothelial growth factor A	6p12	1(0/1/0)	IDA[18440775]
IL16	interleukin 16 (lymphocyte chemoattractant factor)	15q26.3	1(0/0/1)
CMTM8	CKLF-like MARVEL transmembrane domain containing 8	3p22.2	1(1/0/0)

Genes from other sources (count: 16)

Approved Symbol	Approved Name	Source	Evidence[PMID]
IL17D	interleukin 17D	Mapped by significant region
TNFSF18	tumor necrosis factor (ligand) superfamily, member 18	Mapped by significant region
GREM1	gremlin 1	Mapped by CNV; Mapped by significant region
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	Mapped by significant region
INHA	inhibin, alpha	Mapped by significant region	TAS[12456957]
CTF1	cardiotrophin 1	Mapped by CNV
IL17C	interleukin 17C	Mapped by significant region
CLCF1	cardiotrophin-like cytokine factor 1	Mapped by significant region	IDA[10966616]; NAS[10500198]
MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	Mapped by CNV	IDA[12782713]
TNFSF15	tumor necrosis factor (ligand) superfamily, member 15	Mapped by significant region
SCGB3A1	secretoglobin, family 3A, member 1	Mapped by CNV	NAS[11481438]
TNFSF4	tumor necrosis factor (ligand) superfamily, member 4	Mapped by significant region
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	Mapped by significant region	IDA[1674604]
IL18	interleukin 18 (interferon-gamma-inducing factor)	Mapped by significant region	TAS[11598150]
C1QTNF4	C1q and tumor necrosis factor related protein 4	Mapped by LD-proxy
IL6	interleukin 6 (interferon, beta 2)	Mapped by significant region	IDA[3023045]; NAS[10443688]