ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0005764
Name	lysosome
Type	Cellular Component
No. of Genes in ADHDgene	31
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 31)

Literature-origin genes (count: 4)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
ANK3	ankyrin 3, node of Ranvier (ankyrin G)	10q21	1(0/1/0)
STS	steroid sulfatase (microsomal), isozyme S	Xp22.32	3(2/1/0)	TAS[2668275]
ADRB2	adrenergic, beta-2-, receptor, surface	5q31-q32	2(1/1/0)	TAS[9507004]
TSPAN8	tetraspanin 8	12q14.1-q21.1	1(0/1/0)	TAS[8661157]

Genes from other sources (count: 27)

Approved Symbol	Approved Name	Source	Evidence[PMID]
GJA1	gap junction protein, alpha 1, 43kDa	Mapped by significant region
RAB27A	RAB27A, member RAS oncogene family	Mapped by LD-proxy	IDA[15548590]
USE1	unconventional SNARE in the ER 1 homolog (S. cerevisiae)	Mapped by PBA pathway	ISS[16354670]
CCDC115	coiled-coil domain containing 115	Mapped by significant region
RPTOR	regulatory associated protein of MTOR, complex 1	Mapped by LD-proxy
VPS33B	vacuolar protein sorting 33 homolog B (yeast)	Mapped by LD-proxy	IDA[15052268]
CTSF	cathepsin F	Mapped by significant region	TAS[9822672]
SIAE	sialic acid acetylesterase	Mapped by significant region
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	Mapped by significant region
UNC93B1	unc-93 homolog B1 (C. elegans)	Mapped by significant region
PON2	paraoxonase 2	Mapped by PBA pathway
NPC1	Niemann-Pick disease, type C1	Mapped by significant region
DOC2A	double C2-like domains, alpha	Mapped by CNV
LAMTOR1	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1	Mapped by significant region
TPP1	tripeptidyl peptidase I	Mapped by CNV	IDA[15317752]; IMP[9295267]
ZNRF1	zinc and ring finger 1	Mapped by significant region
NAAA	N-acylethanolamine acid amidase	Mapped by CNV
SQSTM1	sequestosome 1	Mapped by CNV
TYR	tyrosinase (oculocutaneous albinism IA)	Mapped by significant region	TAS[11092760]
UVRAG	UV radiation resistance associated gene	Mapped by significant region	IDA[19270696]
SYT7	synaptotagmin VII	Mapped by significant region
RAB14	RAB14, member RAS oncogene family	Mapped by PBA pathway; Mapped by significant region
KIAA1324	KIAA1324	Mapped by CNV
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	Mapped by significant region
CTSC	cathepsin C	Mapped by significant region	TAS[7665576]
PRDX6	peroxiredoxin 6	Mapped by PBA pathway; Mapped by significant region
PRCP	prolylcarboxypeptidase (angiotensinase C)	Mapped by significant region