ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	TSHZ2
Previous Symbol	C20orf17, ZNF218
Symbol Alias	ZABC2, OVC10-2, TSH2
Approved Name	teashirt zinc finger homeobox 2
Previous Name	chromosome 20 open reading frame 17, "zinc finger protein 218", "teashirt family zinc finger 2"
Location	20q13.2
Position	chr20:51588946-52111869, +
External Links	HGNC: 13010 Entrez Gene: 128553 Ensembl: ENSG00000182463 UCSC: uc002xwo.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by LD-proxy; Mapped by literature SNP

Gene related studies (count: 0)

Gene related SNPs (count: 4)

Literature-origin SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs10485813	Chr20:51583983(Fwd)	upstream_gene_variant	1(0/0/1)

LD-proxies (count: 3)

rs_ID	Location	Functional Annotation
rs11906596	Chr20:51584540(Fwd)	upstream_gene_variant
rs13040133	Chr20:51585125(Fwd)	upstream_gene_variant
rs11908686	Chr20:51584562(Fwd)	upstream_gene_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 6)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 6)

ID	Name	Type	No. of Genes in ADHDgene
GO:0043565	sequence-specific DNA binding	Molecular Function	72
GO:0007275	multicellular organismal development	Biological Process	71
GO:0008270	zinc ion binding	Molecular Function	323
GO:0005634	nucleus	Cellular Component	770
GO:0006351	transcription, DNA-dependent	Biological Process	247
GO:0003700	sequence-specific DNA binding transcription factor activity	Molecular Function	132

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with TSHZ2 (count: 9)

Gene Symbol	Pathway Count	Pathway List
LMX1B	6	sequence-specific DNA binding; multicellular organismal development; zinc ion binding; nucleus; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity;
HOXA1	5	sequence-specific DNA binding; multicellular organismal development; nucleus; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity;
HOXA9	5	sequence-specific DNA binding; multicellular organismal development; nucleus; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity;
HOXB1	5	sequence-specific DNA binding; multicellular organismal development; nucleus; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity;
IKZF1	5	sequence-specific DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity;
LHX2	5	sequence-specific DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity;
LHX6	5	sequence-specific DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity;
PRDM1	5	sequence-specific DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity;
ZNF24	5	sequence-specific DNA binding; zinc ion binding; nucleus; transcription, DNA-dependent; sequence-specific DNA binding transcription factor activity;

Genes shared at least 2 KEGG pathways with TSHZ2 (count: 0)

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Region: chr20:51588946..52111869 View in gBrowse