ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

KEGG Pathway Report

Basic Info

ID	hsa00230
Name	Purine metabolism
No. of Genes in ADHDgene	22
Source	Pathway by Database Search

Pathway related genes in ADHDgene (count: 22)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
FHIT	fragile histidine triad gene	3p14.2	1(0/0/1)

Genes from other sources (count: 21)

Approved Symbol	Approved Name	Location	Source
ITPA	inosine triphosphatase (nucleoside triphosphate pyrophosphatase)	20p	Mapped by CNV
PDE4D	phosphodiesterase 4D, cAMP-specific	5q12	Mapped by CNV
ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	2q35	Mapped by significant region
POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)	11q13	Mapped by significant region
POLD3	polymerase (DNA-directed), delta 3, accessory subunit	11q14	Mapped by significant region
APRT	adenine phosphoribosyltransferase	16q24	Mapped by significant region
POLD4	polymerase (DNA-directed), delta 4	11q13	Mapped by significant region
POLE3	polymerase (DNA directed), epsilon 3 (p17 subunit)	9q33	Mapped by significant region
POLR2G	polymerase (RNA) II (DNA directed) polypeptide G	11q13.1	Mapped by significant region
GMPR2	guanosine monophosphate reductase 2	14q11.2	Mapped by significant region
POLR3E	polymerase (RNA) III (DNA directed) polypeptide E (80kD)	16p12	Mapped by CNV; Mapped by significant region
NT5M	5',3'-nucleotidase, mitochondrial	17p11.2	Mapped by significant region
RRM2	ribonucleotide reductase M2	2p25-p24	Mapped by significant region
PDE2A	phosphodiesterase 2A, cGMP-stimulated	11q13.1-q14.1	Mapped by significant region
ENPP3	ectonucleotide pyrophosphatase/phosphodiesterase 3	6q22	Mapped by significant region
POLE	polymerase (DNA directed), epsilon	12q24.3	Mapped by CNV
POLR1A	polymerase (RNA) I polypeptide A, 194kDa	2p11.2	Mapped by CNV
GUCY1A2	guanylate cyclase 1, soluble, alpha 2	11q21-q22	Mapped by significant region
ADCY4	adenylate cyclase 4	14q11.2	Mapped by significant region
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	6q22-q23	Mapped by significant region
PDE7B	phosphodiesterase 7B	6q23-q24	Mapped by significant region