ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0006665
Name sphingolipid metabolic process
Type biological process
No. of Genes in ADHDgene  17
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 17)

Literature-origin genes (count: 4)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
ARSB arylsulfatase B 5q14.1 1(0/0/1) TAS
STS steroid sulfatase (microsomal), isozyme S Xp22.32 3(2/1/0) TAS
PRKD1 protein kinase D1 14q11 1(0/1/0) TAS
TH tyrosine hydroxylase 11p15.5 7(2/5/0) IEA

Genes from other sources Help (count: 13)

Approved Symbol Approved Name Source Evidence[PMID]
NEU3 sialidase 3 (membrane sialidase) Mapped by significant region TAS
SERINC1 serine incorporator 1 Mapped by significant region ISS
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 Mapped by PBA pathway TAS
FA2H fatty acid 2-hydroxylase Mapped by significant region IEA
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 Mapped by CNV TAS
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) Mapped by significant region; Mapped by PBA pathway TAS
UGCG UDP-glucose ceramide glucosyltransferase Mapped by significant region TAS
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal Mapped by CNV; Mapped by PBA pathway TAS
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) Mapped by PBA pathway TAS
ARSJ arylsulfatase family, member J Mapped by CNV TAS
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 Mapped by significant region TAS
ACER3 alkaline ceramidase 3 Mapped by significant region TAS
SUMF1 sulfatase modifying factor 1 Mapped by CNV TAS