ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0042220
Name	response to cocaine
Type	Biological Process
No. of Genes in ADHDgene	11
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 11)

Literature-origin genes (count: 9)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
SLC6A1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	3p25-p24	1(0/1/0)
SLC18A2	solute carrier family 18 (vesicular monoamine), member 2	10q25	2(0/2/0)
DRD5	dopamine receptor D5	4p16.1	22(14/6/2)
DRD3	dopamine receptor D3	3q13.3	8(1/7/0)	IEP[10415668]
DRD2	dopamine receptor D2	11q22-q23	10(3/7/0)
OXTR	oxytocin receptor	3p25	1(0/1/0)
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	5p15.3	68(42/25/1)
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	6q13	13(5/8/0)
CNR1	cannabinoid receptor 1 (brain)	6q14-q15	1(1/0/0)

Genes from other sources (count: 2)

Approved Symbol	Approved Name	Source	Evidence[PMID]
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	Mapped by CNV; Mapped by PBA pathway
TACR3	tachykinin receptor 3	Mapped by CNV