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- Genome-wide Association Studies of ADHD
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- Data Summary
GO Report
Basic Info
| ID | GO:0048167 |
|---|---|
| Name | regulation of synaptic plasticity |
| Type | Biological Process |
| No. of Genes in ADHDgene | 9 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 9)
Literature-origin genes (count: 4)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| CNTN4 | contactin 4 | 3p26.3 | 1(1/0/0) | TAS[15106122] |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 12p12 | 1(1/0/0) | |
| BAIAP2 | BAI1-associated protein 2 | 17q25 | 1(1/0/0) | |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 16p13.2 | 3(1/2/0) |
Genes from other sources (count: 5)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | Mapped by PBA pathway | |
| P2RX3 | purinergic receptor P2X, ligand-gated ion channel, 3 | Mapped by significant region | |
| CTNND2 | catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) | Mapped by CNV | |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | Mapped by LD-proxy; Mapped by literature SNP | |
| ADORA2A | adenosine A2a receptor | Mapped by CNV |