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- Data Summary
GO Report
Basic Info
| ID | GO:0002020 |
|---|---|
| Name | protease binding |
| Type | Molecular Function |
| No. of Genes in ADHDgene | 13 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 13)
Literature-origin genes (count: 2)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 5p15.3 | 68(42/25/1) | |
| FURIN | furin (paired basic amino acid cleaving enzyme) | 15q26.1 | 1(0/0/1) | IPI[14744861] |
Genes from other sources (count: 11)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| UBC | ubiquitin C | Mapped by CNV | |
| SERPINC1 | serpin peptidase inhibitor, clade C (antithrombin), member 1 | Mapped by significant region | IPI[15853774] |
| BDKRB2 | bradykinin receptor B2 | Mapped by PBA pathway | IPI[17077303] |
| PANX1 | pannexin 1 | Mapped by significant region | |
| MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | Mapped by significant region | |
| NFRKB | nuclear factor related to kappaB binding protein | Mapped by significant region | IPI[18922472] |
| FADD | Fas (TNFRSF6)-associated via death domain | Mapped by significant region | IPI[9208847] |
| CHL1 | cell adhesion molecule with homology to L1CAM (close homolog of L1) | Mapped by CNV | |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | Mapped by significant region | IPI[18223652] |
| INS | insulin | Mapped by literature SNP | |
| RYR1 | ryanodine receptor 1 (skeletal) | Mapped by PBA pathway |