ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0060134
Name prepulse inhibition
Type Biological Process
No. of Genes in ADHDgene  10
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 10)

Literature-origin genes (count: 7)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 5p15.3 68(42/25/1)
GRID2 glutamate receptor, ionotropic, delta 2 4q22 1(0/0/1)
DRD2 dopamine receptor D2 11q22-q23 10(3/7/0)
NRXN1 neurexin 1 2p16.3 1(0/1/0) ISS[19822762]
DRD3 dopamine receptor D3 3q13.3 8(1/7/0) IMP[18325483]
DRD1 dopamine receptor D1 5q34-q35 8(5/3/0)
CTNNA2 catenin (cadherin-associated protein), alpha 2 2p12-p11.1 2(1/1/0)

Genes from other sources Help (count: 3)

Approved Symbol Approved Name Source Evidence[PMID]
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A Mapped by significant region
FABP7 fatty acid binding protein 7, brain Mapped by significant region
ADORA2A adenosine A2a receptor Mapped by CNV