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- Data Summary
GO Report
Basic Info
| ID | GO:0043406 |
|---|---|
| Name | positive regulation of MAP kinase activity |
| Type | Biological Process |
| No. of Genes in ADHDgene | 10 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 10)
Literature-origin genes (count: 3)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| VEGFA | vascular endothelial growth factor A | 6p12 | 1(0/1/0) | IDA[18440775] |
| HTR2A | 5-hydroxytryptamine (serotonin) receptor 2A | 13q14-q21 | 12(6/6/0) | |
| ADRA2A | adrenergic, alpha-2A-, receptor | 10q24-q26 | 12(4/8/0) | IDA[19477270] |
Genes from other sources (count: 7)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | Mapped by LD-proxy | IDA[10572067] |
| PDCD10 | programmed cell death 10 | Mapped by CNV | IDA[17360971] |
| ILK | integrin-linked kinase | Mapped by CNV | |
| TPD52L1 | tumor protein D52-like 1 | Mapped by significant region | IDA[14761963] |
| NOX4 | NADPH oxidase 4 | Mapped by significant region | |
| MIF | macrophage migration inhibitory factor (glycosylation-inhibiting factor) | Mapped by CNV | |
| PIK3CG | phosphoinositide-3-kinase, catalytic, gamma polypeptide | Mapped by CNV | IDA[12507995] |