ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0090090
Name	negative regulation of canonical Wnt receptor signaling pathway
Type	Biological Process
No. of Genes in ADHDgene	14
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 14)

Literature-origin genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
GSK3B	glycogen synthase kinase 3 beta	3q13.3	1(1/0/0)	TAS[19366350]
DACT1	dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)	14q22.3	1(0/1/0)
ISL1	ISL LIM homeobox 1	5q11.2	1(0/1/0)

Genes from other sources (count: 11)

Approved Symbol	Approved Name	Source	Evidence[PMID]
WNT11	wingless-type MMTV integration site family, member 11	Mapped by significant region
APC	adenomatous polyposis coli	Mapped by LD-proxy; Mapped by PBA pathway	IGI[12952940]
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	Mapped by significant region
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	Mapped by significant region	IMP[12805222]
CTNND1	catenin (cadherin-associated protein), delta 1	Mapped by significant region
INVS	inversin	Mapped by significant region	IDA[18371931]
LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)	Mapped by PBA pathway
ROR2	receptor tyrosine kinase-like orphan receptor 2	Mapped by significant region
DAB2IP	DAB2 interacting protein	Mapped by significant region
GREM1	gremlin 1	Mapped by CNV; Mapped by significant region	IDA[15539560]
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	Mapped by significant region