ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0045121
Name	membrane raft
Type	Cellular Component
No. of Genes in ADHDgene	22
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 22)

Literature-origin genes (count: 5)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
HK1	hexokinase 1	10q22	1(0/1/0)
FURIN	furin (paired basic amino acid cleaving enzyme)	15q26.1	1(0/0/1)	IDA[17010968]
SLC6A4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	17q11.2	25(13/12/0)	IDA[16870614]
ITGA1	integrin, alpha 1	5q11.1	1(0/1/0)
GSK3B	glycogen synthase kinase 3 beta	3q13.3	1(1/0/0)

Genes from other sources (count: 17)

Approved Symbol	Approved Name	Source	Evidence[PMID]
PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta	Mapped by CNV
MS4A2	membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)	Mapped by PBA pathway; Mapped by significant region
THY1	Thy-1 cell surface antigen	Mapped by significant region	NAS[15093746]
GJA1	gap junction protein, alpha 1, 43kDa	Mapped by significant region
ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	Mapped by CNV; Mapped by significant region	IDA[15469992]
FADD	Fas (TNFRSF6)-associated via death domain	Mapped by significant region
ADAM17	ADAM metallopeptidase domain 17	Mapped by significant region	IDA[17010968]
RTN4RL2	reticulon 4 receptor-like 2	Mapped by significant region
TNR	tenascin R (restrictin, janusin)	Mapped by significant region
LAMTOR1	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1	Mapped by significant region
TRPC1	transient receptor potential cation channel, subfamily C, member 1	Mapped by PBA pathway
UMOD	uromodulin	Mapped by significant region
ARID3C	AT rich interactive domain 3C (BRIGHT-like)	Mapped by LD-proxy
CAV3	caveolin 3	Mapped by LD-proxy; Mapped by literature SNP
NPC1	Niemann-Pick disease, type C1	Mapped by significant region
STOM	stomatin	Mapped by significant region	IDA[12130500]
P2RX3	purinergic receptor P2X, ligand-gated ion channel, 3	Mapped by significant region