ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0030036
Name actin cytoskeleton organization
Type biological process
No. of Genes in ADHDgene  23
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 23)

Literature-origin genes (count: 2)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
ADRA2A adrenoceptor alpha 2A 10q25.2 13(4/9/0) TAS[9624180]
PRKG1 protein kinase, cGMP-dependent, type I 10q11.2 2(0/1/1) TAS[10851246]

Genes from other sources Help (count: 21)

Approved Symbol Approved Name Source Evidence[PMID]
FGD3 FYVE, RhoGEF and PH domain containing 3 Mapped by significant region ISS
CORO1B coronin, actin binding protein, 1B Mapped by significant region IBA
SPIRE1 spire-type actin nucleation factor 1 Mapped by CNV IMP
CORO2A coronin, actin binding protein, 2A Mapped by significant region IBA
TAOK2 TAO kinase 2 Mapped by CNV IDA[10660600]
MON2 MON2 homolog (S. cerevisiae) Mapped by PBA pathway IBA
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) Mapped by PBA pathway ISS[10729324]
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 Mapped by significant region; Mapped by PBA pathway IDA[10430899]
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa Mapped by significant region TAS[9359840]
CORO7 coronin 7 Mapped by significant region IRD
KLHL1 kelch-like family member 1 Mapped by CNV NAS[10888605]
PDPK1 3-phosphoinositide dependent protein kinase-1 Mapped by significant region TAS[10792047]
ARFIP2 ADP-ribosylation factor interacting protein 2 Mapped by CNV IMP[9312003]
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 Mapped by significant region IDA[12071859]
TMSB4Y thymosin beta 4, Y-linked Mapped by PBA pathway IEA
CORO1A coronin, actin binding protein, 1A Mapped by CNV IMP[17442961]
SPIRE2 spire-type actin nucleation factor 2 Mapped by significant region IMP
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 Mapped by significant region IEA
CFL1 cofilin 1 (non-muscle) Mapped by significant region TAS[10436159]
FMN1 formin 1 Mapped by CNV; Mapped by significant region IEA
NF2 neurofibromin 2 (merlin) Mapped by PBA pathway IMP[9537418]