ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0016055
Name	Wnt receptor signaling pathway
Type	Biological Process
No. of Genes in ADHDgene	20
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 20)

Literature-origin genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
DRD2	dopamine receptor D2	11q22-q23	10(3/7/0)
DACT1	dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)	14q22.3	1(0/1/0)

Genes from other sources (count: 18)

Approved Symbol	Approved Name	Source	Evidence[PMID]
TGFB1I1	transforming growth factor beta 1 induced transcript 1	Mapped by PBA pathway
PYGO1	pygopus homolog 1 (Drosophila)	Mapped by LD-proxy; Mapped by literature SNP
FZD4	frizzled family receptor 4	Mapped by significant region	IDA[17955262]
USP34	ubiquitin specific peptidase 34	Mapped by LD-proxy
AMOTL1	angiomotin like 1	Mapped by significant region
PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	Mapped by significant region	TAS[18784435]
WWOX	WW domain containing oxidoreductase	Mapped by significant region
DDB1	damage-specific DNA binding protein 1, 127kDa	Mapped by significant region
HBP1	HMG-box transcription factor 1	Mapped by CNV
RNF146	ring finger protein 146	Mapped by significant region
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	Mapped by significant region
MARK2	MAP/microtubule affinity-regulating kinase 2	Mapped by significant region
INVS	inversin	Mapped by significant region
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	Mapped by significant region
CELSR2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	Mapped by CNV
CTNND1	catenin (cadherin-associated protein), delta 1	Mapped by significant region
RNF138	ring finger protein 138	Mapped by significant region
LRP5	low density lipoprotein receptor-related protein 5	Mapped by CNV; Mapped by significant region	IDA[17955262]