ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0090090
Name negative regulation of canonical Wnt receptor signaling pathway
Type biological process
No. of Genes in ADHDgene  16
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 16)

Literature-origin genes (count: 3)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
ISL1 ISL LIM homeobox 1 5q11.2 1(0/1/0) IEA
DACT1 dishevelled-binding antagonist of beta-catenin 1 14q22.3 1(0/1/0) IEA
GSK3B glycogen synthase kinase 3 beta 3q13.3 1(1/0/0) TAS[19366350]

Genes from other sources Help (count: 13)

Approved Symbol Approved Name Source Evidence[PMID]
CDH2 cadherin 2, type 1, N-cadherin (neuronal) Mapped by significant region IEA
CTNND1 catenin (cadherin-associated protein), delta 1 Mapped by significant region IMP
LATS2 large tumor suppressor kinase 2 Mapped by significant region IMP
INVS inversin Mapped by significant region IDA[18371931]
GREM1 gremlin 1, DAN family BMP antagonist Mapped by CNV; Mapped by significant region IDA[15539560]
LATS1 large tumor suppressor kinase 1 Mapped by PBA pathway IMP
WNT11 wingless-type MMTV integration site family, member 11 Mapped by significant region IMP
APC adenomatous polyposis coli Mapped by LD-proxy; Mapped by PBA pathway IGI[12952940]
DAB2IP DAB2 interacting protein Mapped by significant region IMP
AXIN1 axin 1 Mapped by significant region IBA
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) Mapped by significant region IMP[12805222]
ROR2 receptor tyrosine kinase-like orphan receptor 2 Mapped by significant region IEA
NKD2 naked cuticle homolog 2 (Drosophila) Mapped by significant region IDA; IMP[15687260]