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- Data Summary
GO Report
Basic Info
| ID | GO:0006665 |
|---|---|
| Name | sphingolipid metabolic process |
| Type | Biological Process |
| No. of Genes in ADHDgene | 16 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 16)
Literature-origin genes (count: 2)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| TH | tyrosine hydroxylase | 11p15.5 | 7(2/5/0) | |
| STS | steroid sulfatase (microsomal), isozyme S | Xp22.32 | 3(2/1/0) |
Genes from other sources (count: 14)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) | Mapped by PBA pathway | |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 | Mapped by CNV | |
| ARSJ | arylsulfatase family, member J | Mapped by CNV | |
| SERINC1 | serine incorporator 1 | Mapped by significant region | |
| SMPD4 | sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) | Mapped by PBA pathway; Mapped by significant region | |
| SPTLC1 | serine palmitoyltransferase, long chain base subunit 1 | Mapped by significant region | |
| NEU3 | sialidase 3 (membrane sialidase) | Mapped by significant region | |
| UGCG | UDP-glucose ceramide glucosyltransferase | Mapped by significant region | |
| SUMF1 | sulfatase modifying factor 1 | Mapped by CNV | |
| FA2H | fatty acid 2-hydroxylase | Mapped by significant region | |
| ACER3 | alkaline ceramidase 3 | Mapped by significant region | |
| PRKD1 | protein kinase D1 | Mapped by significant region | |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | Mapped by CNV; Mapped by PBA pathway | |
| ENPP7 | ectonucleotide pyrophosphatase/phosphodiesterase 7 | Mapped by PBA pathway |