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- Data Summary
GO Report
Basic Info
| ID | GO:0007169 |
|---|---|
| Name | transmembrane receptor protein tyrosine kinase signaling pathway |
| Type | Biological Process |
| No. of Genes in ADHDgene | 16 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 16)
Literature-origin genes (count: 4)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| NGF | nerve growth factor (beta polypeptide) | 1p13.1 | 2(2/0/0) | |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 9q22.1 | 1(1/0/0) | |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 3p21-p14 | 1(0/0/1) | TAS[8382771] |
| NTF3 | neurotrophin 3 | 12p13 | 3(1/2/0) |
Genes from other sources (count: 12)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| GAB2 | GRB2-associated binding protein 2 | Mapped by significant region | IDA[19172738] |
| MUSK | muscle, skeletal, receptor tyrosine kinase | Mapped by significant region | TAS[7546737] |
| FLT4 | fms-related tyrosine kinase 4 | Mapped by CNV | TAS[10835628] |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | Mapped by significant region | TAS[8530500] |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | Mapped by significant region | TAS[8808684] |
| ROS1 | c-ros oncogene 1 , receptor tyrosine kinase | Mapped by significant region | |
| ROR2 | receptor tyrosine kinase-like orphan receptor 2 | Mapped by significant region | |
| BDKRB2 | bradykinin receptor B2 | Mapped by PBA pathway | TAS[10653985] |
| AHI1 | Abelson helper integration site 1 | Mapped by significant region | |
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | Mapped by LD-proxy | IDA[7514177]; TAS[7556068] |
| ADORA2A | adenosine A2a receptor | Mapped by CNV | |
| STAP1 | signal transducing adaptor family member 1 | Mapped by significant region |