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- Data Summary
GO Report
Basic Info
| ID | GO:0007179 |
|---|---|
| Name | transforming growth factor beta receptor signaling pathway |
| Type | Biological Process |
| No. of Genes in ADHDgene | 14 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 14)
Literature-origin genes (count: 3)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| XPO1 | exportin 1 (CRM1 homolog, yeast) | 2p15 | 1(0/0/1) | |
| ARRB2 | arrestin, beta 2 | 17p13 | 1(1/0/0) | IDA[12958365] |
| FURIN | furin (paired basic amino acid cleaving enzyme) | 15q26.1 | 1(0/0/1) |
Genes from other sources (count: 11)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| NCOR1 | nuclear receptor corepressor 1 | Mapped by significant region | |
| UBC | ubiquitin C | Mapped by CNV | |
| MEN1 | multiple endocrine neoplasia I | Mapped by significant region | |
| UBB | ubiquitin B | Mapped by significant region | |
| NCOR2 | nuclear receptor corepressor 2 | Mapped by CNV | |
| PTPRK | protein tyrosine phosphatase, receptor type, K | Mapped by CNV; Mapped by significant region | IDA[15899872] |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like | Mapped by significant region | |
| TGFBR1 | transforming growth factor, beta receptor 1 | Mapped by significant region | IC[1326540]; IDA[9389648]; IMP[1333888] |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | Mapped by significant region | |
| LTBP3 | latent transforming growth factor beta binding protein 3 | Mapped by significant region | |
| E2F5 | E2F transcription factor 5, p130-binding | Mapped by CNV |