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- Data Summary
GO Report
Basic Info
| ID | GO:0007194 |
|---|---|
| Name | negative regulation of adenylate cyclase activity |
| Type | Biological Process |
| No. of Genes in ADHDgene | 10 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 10)
Literature-origin genes (count: 7)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| DRD3 | dopamine receptor D3 | 3q13.3 | 8(1/7/0) | IDA[7907363] |
| OPRM1 | opioid receptor, mu 1 | 6q24-q25 | 1(1/0/0) | |
| GRM7 | glutamate receptor, metabotropic 7 | 3p26-p25 | 1(1/0/0) | IDA[9473604] |
| DRD4 | dopamine receptor D4 | 11p15.5 | 67(49/18/0) | IDA[7512953] |
| ADRA2A | adrenergic, alpha-2A-, receptor | 10q24-q26 | 12(4/8/0) | ISS[1354394] |
| GRM8 | glutamate receptor, metabotropic 8 | 7q31.3-q32.1 | 1(1/0/0) | TAS[9473604] |
| DRD2 | dopamine receptor D2 | 11q22-q23 | 10(3/7/0) | IDA[2531656] |
Genes from other sources (count: 3)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| LTB4R2 | leukotriene B4 receptor 2 | Mapped by significant region | TAS[10889186] |
| NPR3 | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | Mapped by significant region | |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 | Mapped by significant region | TAS[10328880] |