ADHDgene Database

Gene Report

Basic Info

Approved Symbol	NPR3
Previous Symbol	NPRC, ANPRC, C5orf23
Symbol Alias	GUCY2B, FLJ14054
Approved Name	natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
Previous Name	chromosome 5 open reading frame 23
Location	5p14-p13
Position	chr5:32689176-32787256, +
External Links	HGNC: 7945 Entrez Gene: 4883 Ensembl: ENSG00000113389 UCSC: uc003jhu.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
5p13	chr5:28900000-42500000	3 (1/1/1)

Gene related GO terms (count: 15)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0001501	skeletal system development	Biological Process		16
GO:0002158	osteoclast proliferation	Biological Process		1
GO:0005887	integral to plasma membrane	Cellular Component	IC[1660465]	220
GO:0008528	G-protein coupled peptide receptor activity	Molecular Function		2
GO:0016941	natriuretic peptide receptor activity	Molecular Function	IDA[1660465]	1
GO:0017046	peptide hormone binding	Molecular Function		5
GO:0033688	regulation of osteoblast proliferation	Biological Process		1
GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway	Biological Process		6
GO:0007194	negative regulation of adenylate cyclase activity	Biological Process		10
GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway	Biological Process		12
GO:0008217	regulation of blood pressure	Biological Process		8
GO:0051000	positive regulation of nitric-oxide synthase activity	Biological Process		3
GO:0042803	protein homodimerization activity	Molecular Function		113
GO:0042562	hormone binding	Molecular Function	IPI[1660465]	4
GO:0035810	positive regulation of urine volume	Biological Process		3

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with NPR3 (count: 0)

Genes shared at least 2 KEGG pathways with NPR3 (count: 0)

View in gBrowse

Region: chr5:32689176..32787256 View in gBrowse