ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0007194
Name negative regulation of adenylate cyclase activity
Type biological process
No. of Genes in ADHDgene  10
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 10)

Literature-origin genes (count: 7)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
OPRM1 opioid receptor, mu 1 6q24-q25 1(1/0/0) ISS
DRD2 dopamine receptor D2 11q22-q23 10(3/7/0) IDA[2531656]; IEA
GRM7 glutamate receptor, metabotropic 7 3p26-p25 3(2/1/0) IDA[9473604]
DRD4 dopamine receptor D4 11p15.5 67(49/18/0) IDA[7512953]
GRM8 glutamate receptor, metabotropic 8 7q31.3-q32.1 1(1/0/0) TAS[9473604]
ADRA2A adrenoceptor alpha 2A 10q25.2 13(4/9/0) ISS[1354394]
DRD3 dopamine receptor D3 3q13.3 8(1/7/0) IDA[7907363]

Genes from other sources Help (count: 3)

Approved Symbol Approved Name Source Evidence[PMID]
LTB4R2 leukotriene B4 receptor 2 Mapped by significant region TAS[10889186]
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 Mapped by significant region TAS[10328880]
NPR3 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) Mapped by significant region IEA