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- Data Summary
GO Report
Basic Info
| ID | GO:0007229 |
|---|---|
| Name | integrin-mediated signaling pathway |
| Type | Biological Process |
| No. of Genes in ADHDgene | 10 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 10)
Literature-origin genes (count: 3)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 17p13 | 1(0/0/1) | |
| ITGA1 | integrin, alpha 1 | 5q11.1 | 1(0/1/0) | |
| ITGA11 | integrin, alpha 11 | 15q22.3-q23 | 1(0/0/1) |
Genes from other sources (count: 7)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| SYK | spleen tyrosine kinase | Mapped by significant region | NAS[12885943] |
| CTGF | connective tissue growth factor | Mapped by significant region | |
| ILK | integrin-linked kinase | Mapped by CNV | IDA[9366252] |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | Mapped by LD-proxy | |
| BCAR1 | breast cancer anti-estrogen resistance 1 | Mapped by significant region | IDA[8649368] |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | Mapped by CNV | |
| PRKD1 | protein kinase D1 | Mapped by significant region |