ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0007507
Name	heart development
Type	Biological Process
No. of Genes in ADHDgene	23
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 23)

Literature-origin genes (count: 4)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
OXTR	oxytocin receptor	3p25	1(0/1/0)
TH	tyrosine hydroxylase	11p15.5	7(2/5/0)
PTPRJ	protein tyrosine phosphatase, receptor type, J	11p11.2	1(0/1/0)
ADRBK1	adrenergic, beta, receptor kinase 1	11q13	1(0/1/0)

Genes from other sources (count: 19)

Approved Symbol	Approved Name	Source	Evidence[PMID]
TBX1	T-box 1	Mapped by CNV	IMP[14585638]
TXNRD2	thioredoxin reductase 2	Mapped by CNV; Mapped by LD-proxy; Mapped by literature SNP
FGF19	fibroblast growth factor 19	Mapped by significant region
PLCE1	phospholipase C, epsilon 1	Mapped by PBA pathway	TAS[11022047]
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	Mapped by CNV
FOXL1	forkhead box L1	Mapped by significant region
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	Mapped by LD-proxy	TAS[15504738]
GJA1	gap junction protein, alpha 1, 43kDa	Mapped by significant region
ADAM19	ADAM metallopeptidase domain 19	Mapped by significant region
NCOA6	nuclear receptor coactivator 6	Mapped by PBA pathway
NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	Mapped by significant region
TCF25	transcription factor 25 (basic helix-loop-helix)	Mapped by significant region	NAS[16574069]
MED12	mediator complex subunit 12	Mapped by PBA pathway
ATM	ataxia telangiectasia mutated	Mapped by CNV; Mapped by significant region
TGFBR1	transforming growth factor, beta receptor 1	Mapped by significant region
OXCT1	3-oxoacid CoA transferase 1	Mapped by significant region
FOXF1	forkhead box F1	Mapped by significant region	IMP[19500772]
EDNRA	endothelin receptor type A	Mapped by PBA pathway
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	Mapped by significant region