ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0005516
Name	calmodulin binding
Type	Molecular Function
No. of Genes in ADHDgene	32
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 32)

Literature-origin genes (count: 7)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
PCDP1	primary ciliary dyskinesia protein 1 [Validated RefSeq, protein coding gene]	2q14.2	1(0/0/1)
NOS1	nitric oxide synthase 1 (neuronal)	12q14-qter	1(1/0/0)
ATP2B3	ATPase, Ca++ transporting, plasma membrane 3	Xq28	1(0/1/0)
CACNA1C	calcium channel, voltage-dependent, L type, alpha 1C subunit	12p13.3	1(0/1/0)	IPI[15140941]
MYO5B	myosin VB	18q	1(0/1/0)
CAMK1D	calcium/calmodulin-dependent protein kinase ID	10p13	1(0/0/1)
SYT1	synaptotagmin I	12cen-q21	4(2/2/0)

Genes from other sources (count: 25)

Approved Symbol	Approved Name	Source	Evidence[PMID]
RIT2	Ras-like without CAAX 2	Mapped by significant region
STRN3	striatin, calmodulin binding protein 3	Mapped by significant region	NAS[10748158]
CDK5RAP2	CDK5 regulatory subunit associated protein 2	Mapped by significant region
INVS	inversin	Mapped by significant region
TRPV1	transient receptor potential cation channel, subfamily V, member 1	Mapped by PBA pathway
NRGN	neurogranin (protein kinase C substrate, RC3)	Mapped by significant region
PLCB3	phospholipase C, beta 3 (phosphatidylinositol-specific)	Mapped by significant region	IPI[12821674]
MYH11	myosin, heavy chain 11, smooth muscle	Mapped by CNV; Mapped by significant region
MAP6	microtubule-associated protein 6	Mapped by significant region
RYR2	ryanodine receptor 2 (cardiac)	Mapped by CNV; Mapped by PBA pathway	IMP[19220289]
KCNN2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2	Mapped by LD-proxy
EEF2K	eukaryotic elongation factor-2 kinase	Mapped by CNV; Mapped by significant region	IDA[9144159]
MYO7A	myosin VIIA	Mapped by significant region	IMP[15300860]
RYR3	ryanodine receptor 3	Mapped by CNV; Mapped by PBA pathway
IQGAP2	IQ motif containing GTPase activating protein 2	Mapped by CNV
SMTNL1	smoothelin-like 1	Mapped by significant region
CAMK2D	calcium/calmodulin-dependent protein kinase II delta	Mapped by CNV
PLA2G6	phospholipase A2, group VI (cytosolic, calcium-independent)	Mapped by PBA pathway
TRPV5	transient receptor potential cation channel, subfamily V, member 5	Mapped by PBA pathway
TRPV6	transient receptor potential cation channel, subfamily V, member 6	Mapped by PBA pathway	IDA[11278579]
TJP1	tight junction protein 1 (zona occludens 1)	Mapped by CNV; Mapped by significant region
RYR1	ryanodine receptor 1 (skeletal)	Mapped by PBA pathway
MYO15A	myosin XVA	Mapped by significant region
RGS16	regulator of G-protein signaling 16	Mapped by significant region	TAS[10747990]
PHKG2	phosphorylase kinase, gamma 2 (testis)	Mapped by CNV