ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0017124
Name	SH3 domain binding
Type	Molecular Function
No. of Genes in ADHDgene	22
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 22)

Literature-origin genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
BAIAP2	BAI1-associated protein 2	17q25	1(1/0/0)
SH3BP5	SH3-domain binding protein 5 (BTK-associated)	3p24.3	1(0/0/1)
DRD4	dopamine receptor D4	11p15.5	67(49/18/0)	IDA[9843378]

Genes from other sources (count: 19)

Approved Symbol	Approved Name	Source	Evidence[PMID]
GJA1	gap junction protein, alpha 1, 43kDa	Mapped by significant region
RAD9A	RAD9 homolog A (S. pombe)	Mapped by significant region	IPI[11971963]
INPPL1	inositol polyphosphate phosphatase-like 1	Mapped by significant region
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	Mapped by significant region	IPI[9447983]
SYNGAP1	synaptic Ras GTPase activating protein 1	Mapped by LD-proxy; Mapped by literature SNP
ADAM17	ADAM metallopeptidase domain 17	Mapped by significant region
PTTG1	pituitary tumor-transforming 1	Mapped by significant region
BCAR1	breast cancer anti-estrogen resistance 1	Mapped by significant region
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	Mapped by significant region	IPI[12110186]
ILK	integrin-linked kinase	Mapped by CNV
MAPT	microtubule-associated protein tau	Mapped by LD-proxy; Mapped by PBA pathway	IPI[9763511]
ADAM19	ADAM metallopeptidase domain 19	Mapped by significant region
UVRAG	UV radiation resistance associated gene	Mapped by significant region
CABYR	calcium binding tyrosine-(Y)-phosphorylation regulated	Mapped by significant region	NAS[11820818]
DENND1A	DENN/MADD domain containing 1A	Mapped by significant region
SHANK2	SH3 and multiple ankyrin repeat domains 2	Mapped by significant region
FMN1	formin 1	Mapped by CNV; Mapped by significant region
ARHGAP42	Rho GTPase activating protein 42	Mapped by significant region
CYBA	cytochrome b-245, alpha polypeptide	Mapped by significant region	IPI[7938008]