Hot Results
- Quick Search
- Large-scale studies
- Genome-wide Association Studies of ADHD
- Genome-wide Linkage Studies of ADHD
- Genome-wide CNV Analyses of ADHD
- Meta-analysis Studies of ADHD
- Data Summary
GO Report
Basic Info
| ID | GO:0007266 |
|---|---|
| Name | Rho protein signal transduction |
| Type | Biological Process |
| No. of Genes in ADHDgene | 11 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 11)
Literature-origin genes (count: 4)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 12q13.13 | 1(0/0/1) | |
| CDH13 | cadherin 13, H-cadherin (heart) | 16q23.3 | 3(1/1/1) | IMP[15703273] |
| ADRA2A | adrenergic, alpha-2A-, receptor | 10q24-q26 | 12(4/8/0) | TAS[9624180] |
| ADRB1 | adrenergic, beta-1-, receptor | 10q24-q26 | 2(0/2/0) |
Genes from other sources (count: 7)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| CDC42EP5 | CDC42 effector protein (Rho GTPase binding) 5 | Mapped by PBA pathway | |
| RHOD | ras homolog gene family, member D | Mapped by significant region | TAS[9116026] |
| ARHGAP5 | Rho GTPase activating protein 5 | Mapped by significant region | TAS[8537347] |
| CFL1 | cofilin 1 (non-muscle) | Mapped by significant region | TAS[10436159] |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | Mapped by significant region | IDA[12270917] |
| EDNRA | endothelin receptor type A | Mapped by PBA pathway | |
| MCF2L | MCF.2 cell line derived transforming sequence-like | Mapped by CNV |