ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs5569 dbSNP Ensembl
Location chr16:55731835(Fwd)
Variant Alleles G/A
Ancestral Allele G
Functional Annotation downstream_gene_variant; synonymous_variant; upstream_gene_variant.
Consequence to Transcript downstream_gene_variant(ENST00000568529)
synonymous_variant(ENST00000219833; ENST00000379906; ENST00000414754; ENST00000561820; ENST00000566163; ENST00000567238; ENST00000568943)
upstream_gene_variant(ENST00000574918)
No. of Studies 6 (significant: 1; non-significant: 4; trend: 1)
Source Literature-origin

SNP related studies (count: 6)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Sengupta, S. M., 2012 C/T P-value=0.08, Z statistic (allele 1)=1.72 P-value=0.08, Z statistic (allele 1)=1.72 No significant association was found in this study. No significant association was found in this study. Non-significant
Hahn MK, 2009 G:A synonymous SNP in coding region of candidate gene SLC6A2 synonymous SNP in coding region of candidate gene SLC6A2 Trend
Gizer IR, 2009 Meta-analysis model: Fixed: OR=1.06, 95% CI=0.95-1.18, two-t...... Meta-analysis model: Fixed: OR=1.06, 95% CI=0.95-1.18, two-tailed P-value=0.279; Q-statistic: P-value=0.992, I2=0 More... no evidence to suggest an association between this polymorph...... no evidence to suggest an association between this polymorphisms and ADHD More... Non-significant
Cho SC, 2008 G/A allelic TDT P-value=0.954, genotypic TDT P-value=0.955 allelic TDT P-value=0.954, genotypic TDT P-value=0.955 there was no evidence for biased transmission of any of the ...... there was no evidence for biased transmission of any of the alleles More... Non-significant
Hawi, Z., 2012 G:A A P-value=0.0081*, X2=7.01, OR=1.44, 95% CI=1.09-1....... P-value=0.0081*, X2=7.01, OR=1.44, 95% CI=1.09-1.88 More... Nominal associations between ADHD and the marker was observe...... Nominal associations between ADHD and the marker was observed. However, the association did not remain significant after adjusting the p values using 10,000 permutations. More... Significant
Kim JW, 2008 X2=0.147, P-value=0.701, OR=1.04 X2=0.147, P-value=0.701, OR=1.04 not associated with ADHD not associated with ADHD Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 0)


SNPs in LD with rs5569 (count: 4) View in gBrowse (chr16:55718483..55731835 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 4)