ADHDgene Database
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Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs3785157 dbSNP Ensembl
Location Chr16:55729836(Fwd)
Variant Alleles C/T
Ancestral Allele C
Functional Annotation downstream_gene_variant; intron_variant; upstream_gene_variant.
Consequence to Transcript downstream_gene_variant(ENST00000568529)
intron_variant(ENST00000379906; ENST00000414754; ENST00000567238; ENST00000561820; ENST00000568943; ENST00000219833; ENST00000566163)
upstream_gene_variant(ENST00000574918)
No. of Studies 5 (significant: 3; non-significant: 2; trend: 0)
Source Literature-origin

SNP related studies (count: 5)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Xu X, 2005(a) allelic X2 statistic P-value=0.034, TDT P-value=0...... allelic X2 statistic P-value=0.034, TDT P-value=0.04, OR=1.3 More... showed trends for association in the family sample, not sign...... showed trends for association in the family sample, not significant after adjustment for the number of markers analyzed More... Significant
Bobb AJ, 2005 allelic TDT P-value=0.87, OR=1.03 in case-control analysis; ...... allelic TDT P-value=0.87, OR=1.03 in case-control analysis; allelic TDT P-value=0.002, RR=2.28 in family-based analysis More... there was preferential transmission of the T allele to ADHD ...... there was preferential transmission of the T allele to ADHD probands More... Significant
Kim JW, 2008 X2=1.478, P-value=0.224, OR=1.13 X2=1.478, P-value=0.224, OR=1.13 not associated with ADHD not associated with ADHD Non-significant
Hawi, Z., 2012 C:T T P-value=0.0545, X2=3.7, OR=1.3, 95% CI=1.00-1.70 P-value=0.0545, X2=3.7, OR=1.3, 95% CI=1.00-1.70 Nominal associations between ADHD and the marker was observe...... Nominal associations between ADHD and the marker was observed. However, the association did not remain significant after adjusting the p values using 10,000 permutations. More... Non-significant
Ilott NE, 2010 QTDT AT P-value=0.06, X2=3.68, df=1, QTDT AW P-va...... QTDT AT P-value=0.06, X2=3.68, df=1, QTDT AW P-value=0.03, X2=4.65, df=1 at age 2; QTDT AT P-value=0.48, X2=0.37, df=1, QTDT AW P-value=0.04, X2=4.3, df=1 at age 3 More... modest, nominally significant associations in the AW test at...... modest, nominally significant associations in the AW test at ages 2 and 3 More... Significant

SNP related genes (count: 2)

Literature-origin genes (count: 2)

Genes from other sources Help (count: 0)


SNPs in LD with rs3785157 (count: 9) View in gBrowse (chr16:55718483..55731835 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2>=0.8.

Literature-origin SNPs (count: 3)

LD-proxies (count: 6)

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014