ADHDgene Database
  • Hot Results
  • Quick Search
Keyword:
Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs3785143 dbSNP Ensembl
Location Chr16:55695106(Fwd)
Variant Alleles C/T
Ancestral Allele C
Functional Annotation intron_variant.
Consequence to Transcript intron_variant(ENST00000568655; ENST00000561820; ENST00000568943; ENST00000219833; ENST00000566163; ENST00000568529; ENST00000414754; ENST00000379906)
No. of Studies 6 (significant: 5; non-significant: 1; trend: 0)
Source Literature-origin

SNP related studies (count: 6)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Brookes K, 2006 A/G UNPHASED TDT P-value=0.0117; WHAP TDT P-value=0.110 UNPHASED TDT P-value=0.0117; WHAP TDT P-value=0.110 significant association was observed in UNPHASED analysis significant association was observed in UNPHASED analysis Significant
Xu X, 2008(b) TDT P-value=0.02, OR=1.4 in ST1; TDT P-value=0.8, OR=0.93 in...... TDT P-value=0.02, OR=1.4 in ST1; TDT P-value=0.8, OR=0.93 in ST2; TDT P-value=0.02, OR=1.45 in MGH; TDT P-value=0.62, OR=0.85 in Dublin; TDT P-value=0.008, OR=1.27 in TOTAL More... the overall evidence of association was significant across a...... the overall evidence of association was significant across all four datasets More... Significant
Hawi, Z., 2012 C:T C P-value=0.7389, X2=0.11, OR=1.08, 95% CI=0.70-1.6...... P-value=0.7389, X2=0.11, OR=1.08, 95% CI=0.70-1.65 More... The marker did not show significant association with ADHD. The marker did not show significant association with ADHD. Non-significant
Biederman J, 2008 TDT P-value=0.02 for all; TDT P-value=0.37 for transmission ...... TDT P-value=0.02 for all; TDT P-value=0.37 for transmission to male offspring; TDT P-value=0.006, OR=2.11 for transmission to female offspring; TDT P-value=0.101, X2=2.68 for male versus female transmissions More... TDT analysis in the full sample showed nominally significant...... TDT analysis in the full sample showed nominally significant association and the T allele of rs3785143 displayed a stronger effect in females than in males More... Significant
Kim JW, 2008 X2=5.357, P-value=0.02, OR=1.45; X2=11...... X2=5.357, P-value=0.02, OR=1.45; X2=11.6, P-value=0.0006, OR=1.42 in the combined study More... shows positive associations shows positive associations Significant
Sengupta, S. M., 2012 C/T P-value=0.024, Z statistic (allele 1)=2.25 P-value=0.024, Z statistic (allele 1)=2.25 Two of the SNPs (rs3785143 and rs36021) showed a significant...... Two of the SNPs (rs3785143 and rs36021) showed a significant association with ADHD. More... Significant

SNP related genes (count: 2)

Literature-origin genes (count: 2)

Genes from other sources Help (count: 0)


SNPs in LD with rs3785143 (count: 1) View in gBrowse (chr16:55695106..55713088 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2>=0.8.

Literature-origin SNPs (count: 1)

LD-proxies (count: 0)

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014